GLP-1 Cost Questions, Answered
The 20 most-searched GLP-1 cost questions, with short, sourced answers and the 2026 numbers behind them. Every figure ties back to our methodology and price database. Educational only — not medical advice, and prices change, so verify on the provider's own page.
By brand-name drug
How much does Mounjaro cost per month without insurance?
At cash retail without insurance or a savings card, Mounjaro (tirzepatide) runs about $1,135 a month in 2026. Manufacturer savings programs and self-pay vials can lower that, and the same molecule compounded through telehealth typically costs a fraction of it.
How much does Zepbound cost without insurance?
Zepbound (tirzepatide) is roughly $1,086 a month at cash retail. Eli Lilly's LillyDirect self-pay single-dose vials are cheaper — around $349 a month at lower doses — though the price rises with dose.
How much does Wegovy cost without insurance?
Wegovy (semaglutide) is about $1,349 a month at cash retail, the highest sticker of the major GLP-1s. Novo Nordisk's NovoCare self-pay option brings eligible cash-payers down to roughly $499 a month.
How much does Ozempic cost per month?
Ozempic (semaglutide, diabetes-labeled) is about $969 a month at cash retail. It is frequently prescribed off-label for weight, but coverage and price depend on your diagnosis and plan.
How much does the oral semaglutide (Rybelsus / Wegovy pill) cost?
Oral semaglutide at cash retail generally runs around $1,000 or more a month, broadly in line with the injectable brands. Self-pay and savings programs vary by product and dose, so confirm the current price for the specific pill you are prescribed.
By molecule
How much does tirzepatide cost?
It depends entirely on the route. Brand tirzepatide (Mounjaro, Zepbound) is about $1,086–$1,135 a month at cash retail; the compounded median through telehealth is around $199 a month, and the lowest fully-credentialed flat price we track is $186 a month.
How much does semaglutide cost per month?
Brand semaglutide (Wegovy, Ozempic) is about $969–$1,349 a month at cash retail. Compounded semaglutide has a median around $179 a month, with the lowest fully-credentialed flat price at $145 a month and advertised stickers as low as $99.
Compounded options
How much does compounded semaglutide cost?
Compounded semaglutide typically ranges from about $99 to $300 a month. The median is near $179; the lowest fully-credentialed flat plan we track is $145 a month. Compounded versions are not FDA-approved and quality varies by pharmacy, so verify credentials before price.
How much does compounded tirzepatide cost?
Compounded tirzepatide generally ranges from about $99 to $385 a month, with a median near $199 and a lowest fully-credentialed flat price of $186 a month. As with semaglutide, it is not FDA-approved — confirm the pharmacy, prescriber, and testing.
Is compounded GLP-1 cheaper than brand-name?
Yes — usually 80–90% less than brand cash retail. A verified flat compounded plan can run under $200 a month versus roughly $1,000–$1,350 for brand retail. The trade-off is that compounded products are not FDA-approved and consistency depends on the compounding pharmacy.
Why is my price higher than the “from” amount advertised?
Advertised “from” prices usually reflect the lowest starter dose. On tiered-pricing plans, the monthly cost rises as you titrate up to a maintenance dose, so your real annual cost can be hundreds of dollars above the headline. Flat plans charge one price across the full titration.
Insurance & Medicare
How much do GLP-1 medications cost with insurance?
When a plan covers a GLP-1, the typical out-of-pocket copay is about $0–$50 a month, but coverage is far from universal and often requires prior authorization or a qualifying diagnosis. Confirm your specific copay and any step-therapy rules directly with your plan.
Does Medicare cover Ozempic or Wegovy?
Medicare Part D can cover these drugs for an approved medical indication such as type 2 diabetes or, for semaglutide, established cardiovascular disease — but coverage purely for weight loss has historically been restricted by statute. Rules are evolving, so check current Part D formularies and any pending changes.
Does insurance cover compounded GLP-1?
Generally no. Compounded medications are usually not covered by commercial insurance or Medicare, which is part of why patients pay cash for them. That cash price is still typically well below brand retail.
Comparisons & telehealth
Semaglutide vs tirzepatide: which is cheaper?
Compounded semaglutide is usually a little cheaper per month than compounded tirzepatide (roughly $145–$179 vs $186–$199 at the low end). Tirzepatide tends to produce more average weight loss in trials, so “cheaper” and “more effective on average” can point to different drugs.
Zepbound vs Wegovy: which costs less?
At cash retail Zepbound (about $1,086) is somewhat cheaper than Wegovy (about $1,349), and self-pay vial programs differ between the two manufacturers. Compounded versions of either molecule cost far less, often $99–$200 a month.
What is the cheapest GLP-1 medication available?
The cheapest options are compounded semaglutide and tirzepatide. The lowest advertised sticker is around $99 a month; the lowest fully-credentialed flat price we track is $145 a month for semaglutide. Always compare on the maintenance-dose price and 12-month total, not the starter price.
How much do Hims, Ro, and other telehealth GLP-1 programs cost?
Telehealth GLP-1 programs generally charge about $99–$385 a month for compounded medication, plus a consultation fee that ranges from free to roughly $129. Watch for membership fees, lab charges, and dose-based price increases, which can change the real total.
What is the total 12-month cost of a GLP-1 program?
Beyond the medication, a full program can include an initial consult ($100–$300), follow-ups ($50–$150), and periodic labs ($50–$200). All in, a year ranges from roughly $1,200 for the cheapest compounded route to $16,000+ for brand retail — see our 12-month total-cost breakdown.
Sources & how we price
Brand cash-retail figures reflect 2026 U.S. list pricing for Mounjaro, Zepbound, Wegovy, and Ozempic; self-pay figures reflect LillyDirect and NovoCare programs. Compounded ranges and medians come from our verified provider dataset. For the full scoring rubric and “last verified” dates, see our methodology, price database, and the 12-month total-cost breakdown.
Educational content, not medical advice. Compounded semaglutide and tirzepatide are not FDA-approved and are not the same as Wegovy, Ozempic, Zepbound, or Mounjaro. Prices are consolidated from public sources, change frequently, and should be confirmed directly with each provider. Talk to a licensed clinician before starting, stopping, or changing any medication.
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GLP-1 Cost Guide. (2026). GLP-1 Cost Questions, Answered (2026). https://glp1costguide.com/glp1-cost-questions/According to GLP-1 Cost Guide (2026)<a href="https://glp1costguide.com/glp1-cost-questions/">GLP-1 Cost Questions, Answered (2026)</a> — GLP-1 Cost Guide (2026)[GLP-1 Cost Questions, Answered (2026)](https://glp1costguide.com/glp1-cost-questions/) — GLP-1 Cost Guide (2026)Independent & transparent
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